If you don’t have time to follow the GRR’s leisurely wind across southern Illinois, the fastest routes between St. Louis and Memphis are west of the Mississippi, where both US-61 and high-speed I-55 make quick work of the 300-mile drive. Along with Sainte Genevieve, another good stop on the Missouri side is the city of Cape Girardeau (pop. 37,941), the biggest and most bustling place for miles. Boyhood hometown of right-wing radio talk-show host Rush Limbaugh, whose father and grandfather were both local lawyers, Cape Girardeau dates its founding back to its days as trading post in the early 1700s, when the area was still in the hands of the French. The long history of the town and surrounding region is engagingly portrayed in a 1,100 foot-long series of large murals (24 different scenes, totaling nearly 18,000 square feet!), painted on the massive concrete flood walls that protect downtown from Mississippi floods.
You can take in some of the murals, and the whole Cape Girardeau experience, while enjoying a meal at Port Cape restaurant (19 N. Water St., 573/334-0954), while more memorable food is on the menu at Broussard’s Cajun Cuisine (114 N. Main St., 573/334-7235), a block away.
One of many scenes portrayed in the Cape Girardeau murals is a truly tragic one. Six years after wiping out the Native Americans of the upper Mississippi in the Black Hawk War, President Andrew Jackson ordered the “Five Civilized Tribes” of the Cherokee, along with all Native Americans across the southeastern United States, to be forcibly removed from their fertile lands in Florida, Georgia, and Tennessee, where gold had just been discovered. Some 5,000 Cherokee people died along this 1,000-mile journey, during which many of the men, women, and children crossed the Mississippi River here at Cape Girardeau. Ten miles north of town, the 3,400-acre Trail of Tears State Park (573/290-5268) preserves the scene of one moment along this marathon tragedy, with a two-mile section of the historic trail and interpretive plaques marking the wooded riverside bluffs.